Clearside Biomedical, Inc. is a biopharmaceutical company revolutionizing the delivery of therapies to the back of the eye through the suprachoroidal space (SCS®).

Clearside’s SCS injection platform, utilizing the Company’s patented SCS Microinjector®, enables an in-office, repeatable, non-surgical procedure for the targeted and compartmentalized delivery of a wide variety of therapies to the macula, retina, or choroid to potentially preserve and improve vision in patients with sight-threatening eye diseases.

Clearside is developing its own pipeline of small molecule product candidates for administration via its SCS Microinjector. The Company’s lead program, CLS-AX (axitinib injectable suspension), for the treatment of neovascular age-related macular degeneration (wet AMD), is in Phase 2b clinical testing.

Clearside developed and gained approval for its first product, XIPERE® (triamcinolone acetonide injectable suspension) for suprachoroidal use, which is available in the U.S. through a commercial partner.

Clearside also strategically partners its SCS injection platform with companies utilizing other ophthalmic therapeutic innovations.


Clearside’s Suprachoroidal Space (SCS®) Injection Platform

Clearside’s proprietary SCS injection treatment approach offers unprecedented access to the back of the eye where sight-threatening disease often occurs. The company’s unique platform is inherently flexible and intended to work with established medications, new formulations of medicines, as well as future innovations, that can be delivered via suprachoroidal administration.


We are leveraging our SCS injection platform by building an internal research and development pipeline and by creating external collaborations with other companies.


Our extensive patent portfolio provides us with exclusive rights to commercialize pharmacological agents for treatment of eye diseases via suprachoroidal injection. Our drug candidates, SCS Microinjector and method of drug administration into the SCS are protected by multiple U.S., European and international patents broadly directed to the use of the device, administration of any drug into the SCS by injection, as well as specific product candidates.